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DeCS
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Descriptor English:
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Silent Information Regulator Proteins, Saccharomyces cerevisiae
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Descriptor Spanish:
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Proteínas Reguladoras de Información Silente de Saccharomyces cerevisiae
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Descriptor Portuguese:
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Proteínas Reguladoras de Informação Silenciosa de Saccharomyces cerevisiae
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Synonyms English:
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SIR Proteins, S cerevisiae
Silent Information Regulator Proteins, S cerevisiae
Silent Mating Type Information Regulator Protein, S cerevisiae
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Tree Number:
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D12.776.354.750.750
D12.776.660.820
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Definition English:
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A set of nuclear proteins in SACCHAROMYCES CEREVISIAE that are required for the transcriptional repression of the silent mating type loci. They mediate the formation of silenced CHROMATIN and repress both transcription and recombination at other loci as well. They are comprised of 4 non-homologous, interacting proteins, Sir1p, Sir2p, Sir3p, and Sir4p. Sir2p, an NAD-dependent HISTONE DEACETYLASE, is the founding member of the family of SIRTUINS. |
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See Related English:
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Sirtuins
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History Note English:
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2003
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Allowable Qualifiers English:
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Record Number:
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37446
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Unique Identifier:
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D038281
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Occurrence in VHL:
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Similar:
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DeCS
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